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br Materials and methods br Results br Discussion
2021-01-29
Materials and methods Results Discussion In particular, we showed that pancreatic neuroendocrine tumor bromhexine recognize cAMP as a stimulatory signal for cell proliferation. Conversely, cAMP was found to have an inhibitory effect on cell proliferation in bronchial carcinoids cells. The
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In conclusion we for the first time demonstrated
2021-01-29
In conclusion, we for the first time demonstrated the enzyme activity and immunoprotective traits of bioactive recombinant SjCE-2b, which was successfully recovered by protein refolding from inclusion bodies. The results address two essential questions that were undocumented in previous investigatio
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Several eukaryotic E enzymes including BRE RNF
2021-01-29
Several eukaryotic E3 enzymes, including BRE1 [49], RNF8 [50], and RAD18 [24], [51], have been reported to partner with UBE2B in the ubiquitination of various targets. We examined the expression levels of these E3 enzymes in HONE1 and TW01 cells; RAD18 was highly expressed in these Oligomycin Comple
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br Genotype phenotype correlations Genotype phenotype correl
2021-01-28
Genotype-phenotype correlations Genotype-phenotype correlations are limited. Compared with individuals with truncating variants, those with pathogenic missense variants in the adenosine triphosphate binding site had a milder disorder, some with ability to walk unaided, better hand use, and less r
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This paper proposes an acceptance
2021-01-28
This paper proposes an acceptance process and evaluation criteria, specialized for the dedication of indirect COTS SW as well as direct ones. (Step 1) It first recognizes an indirect COTS SW as a target of dedication, unlike EPRI NP-5652/TR-106439. (Step 2) It then determines the safety category of
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Some studies have integrated the use of cloud
2021-01-28
Some studies have integrated the use of cloud computing with user interfaces in the domain of our proposal (i.e. UI). In [24] the authors work with Android devices to achieve more flexibility in the user interfaces by making use of information about the environment (for example, with an ambient ligh
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br Experimental br Results and discussion On the basis
2021-01-28
Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it ZLN005 australia is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promotion of the co
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The underlying assumption of consolidation re
2021-01-28
The underlying assumption of consolidation/re-consolidation is that the hyPerFUsion™ high-fidelity DNA polymerase activity initiated during the acquisition trial/re-consolidation trial continues to persist briefly after completion of the trial and it is during this post-trial period that immediate
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EPAC induces SOCS gene expression in VECs resulting in suppr
2021-01-28
EPAC1 induces SOCS3 gene expression in VECs, resulting in suppression of the JAK–STAT activation initiated by the sIL-6Rα/IL-6 trans-signalling complex [67]. EPAC1 regulates SOCS3 gene induction through the activation of C/EBP and c-Jun transcription factors, which interact directly with the SOCS3 p
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The presence of external NAD
2021-01-28
The presence of external NAD(P)H dehydrogenases (NDE) on the outer surface of the inner mitochondrial membrane enables the mitochondria to oxidize cytosolic NAD(P)H (Moller 2001). A porin (a voltage-dependent anion-selective channel, VDAC) that is abundant in the outer mitochondrial membrane permits
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br Introduction Noncanonical nucleoside triphosphates NTPs s
2021-01-28
Introduction Noncanonical nucleoside triphosphates (NTPs; such as deoxyinosine triphosphate (dITP), deoxyxanthosine triphosphate (dXTP), 8-oxo-deoxyguanosine triphosphate, and 2-oxo-deoxyadenosine triphosphate are produced from oxidation, deamination, or other modifications of canonical nucleotid
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We have performed our MSP analyses as real time
2021-01-28
We have performed our MSP analyses as real-time PCR using SybrGreen (Fig. 2). The results of the beta-actin PCR vary in each sample group because the amount of DNA for bisulfite treatment was adjusted to a constant volume of serum (500μl) rather than to equal amounts of DNA. Because we expected lowe
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A previous report showed that the transfer of the CSF
2021-01-28
A previous report showed that the transfer of the CSF1 gene into tumor 1670 induced TAM infiltration into syngeneic BALB/c mice. High expressions of CSF-1 and CSF-1R in tumor and stromal cells and a high TAM density are known to be correlated with poor prognoses in many cancer types. CSF-1 promotes
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Meanwhile high levels of extraversion have been associated
2021-01-27
Meanwhile, high levels of extraversion have been associated with weaker conditioning and faster pim inhibitor learning (Eysenck, 1970). Similar to neuroticism/anxiety, the role of extraversion for fear conditioning and extinction has found only limited empirical support (Rauch et al., 2005) with se
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Furthermore certain components in the Melanocyte
2021-01-27
Furthermore, certain components in the Melanocyte Growth Medium seem to influence the response to UV radiation [17]: UV-induced effects on tyrosinase activity were less distinct in melanocytes cultured with phorbol 12-myristate 13-acetate [18], which was also an ingredient in our Melanocyte Growth M
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